LL-37
emergingThe only human cathelicidin antimicrobial peptide, providing broad-spectrum defense against bacteria, viruses, and fungi while modulating immune responses.
Overview
LL-37 is a 37-amino acid peptide and the only member of the cathelicidin family found in humans. It is cleaved from its precursor protein hCAP-18 and is expressed in immune cells (neutrophils, macrophages), epithelial cells, and other barrier tissues. It serves as a critical component of the innate immune system.
LL-37 has direct antimicrobial activity against a broad spectrum of pathogens including gram-positive and gram-negative bacteria, enveloped viruses, and fungi. Beyond direct killing, it modulates immune responses by promoting chemotaxis, stimulating angiogenesis, neutralizing endotoxins (LPS), and influencing adaptive immunity. It has been studied for wound healing, infection prevention, and as an adjunct in biofilm-associated infections.
Review LL-37 options
Review LL-37 product information and ordering options from Ascension Peptides.
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Benefits
- ✓Broad-spectrum antimicrobial activity
- ✓Disrupts bacterial biofilms
- ✓Neutralizes endotoxins (LPS)
- ✓Promotes wound healing and angiogenesis
- ✓Modulates innate and adaptive immunity
- ✓Anti-viral properties against enveloped viruses
Side Effects
- ⚠Injection site pain and irritation
- ⚠Potential pro-inflammatory effects at high doses
- ⚠Skin irritation with topical use
- ⚠May exacerbate certain autoimmune conditions
- ⚠Limited human dosing data
- ⚠Possible mast cell activation
Where to Source LL-37
Quality and purity matter with peptides. Only buy from suppliers that provide third-party Certificate of Analysis (COA) testing. Compare verified sources below:
Ascension Peptides
Third-party tested, US-based peptide supplier with COAs on every batch.
Review current supplier documentation before purchasing.
Quick Comparison Guide
🔍 Buying Tips for LL-37
- • Always request Certificate of Analysis (COA) before purchasing
- • Verify the supplier's testing methodology and third-party lab credentials
- • Look for proper cold storage and shipping practices
- • Start with smaller quantities to test supplier quality
- • Join peptide communities for supplier reviews and experiences
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⚠ Research Disclaimer: This information is for educational purposes only and is not medical advice. Consult a qualified healthcare professional before using LL-37 or any peptide. See our full medical disclaimer.
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