Melanotan II

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MT-2MT2Melanotan 2

A synthetic melanocortin peptide that stimulates melanogenesis (tanning) and has notable effects on libido and sexual function.

Category
sexual health
Dosage
0.25-0.5 mg/day (loading), 0.5 mg 1-2x/week (maintenance)
Half-Life
Approximately 33 minutes (but biological effects persist much longer)
Administration
Subcutaneous injection

Overview

Melanotan II is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH) that acts on melanocortin receptors MC1R through MC5R. Originally developed at the University of Arizona as a potential sunless tanning agent, it was found to have significant effects on sexual arousal and erectile function through MC4R activation in the central nervous system.

MT-2 produces a deep, natural-looking tan without UV exposure by stimulating melanocytes to produce more melanin. Its sexual enhancement effects led to the development of PT-141 (bremelanotide), which is an FDA-approved derivative. Despite its popularity in the biohacking community, MT-2 remains unapproved for human use and carries notable side effect risks including nausea and mole darkening.

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Benefits

  • Promotes skin tanning without UV exposure
  • Enhances libido and sexual arousal
  • May improve erectile function
  • Potential appetite suppression
  • Possible photoprotective effects
  • Long-lasting tan with maintenance dosing

Side Effects

  • Nausea (very common, especially initially)
  • Facial flushing
  • Darkening of existing moles (requires monitoring)
  • Spontaneous erections
  • Fatigue and drowsiness
  • Potential risk of melanoma (theoretical, debated)
  • Injection site reactions

Where to Source Melanotan II

Quality and purity matter with peptides. Only buy from suppliers that provide third-party Certificate of Analysis (COA) testing. Compare verified sources below:

TOP CHOICE

Ascension Peptides

Third-party tested, US-based peptide supplier with COAs on every batch.

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Commission Rate
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Customer support

Quick Comparison Guide

Quality
COA + 3rd party testing required
Purity
≥95% minimum standard
Storage
Lyophilized powder preferred
Shipping
Cold chain when needed

🔍 Buying Tips for Melanotan II

  • • Always request Certificate of Analysis (COA) before purchasing
  • • Verify the supplier's testing methodology and third-party lab credentials
  • • Look for proper cold storage and shipping practices
  • • Start with smaller quantities to test supplier quality
  • • Join peptide communities for supplier reviews and experiences

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⚠ Research Disclaimer: This information is for educational purposes only and is not medical advice. Consult a qualified healthcare professional before using Melanotan II or any peptide. See our full medical disclaimer.

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